Autism Research Database - Principal Investigator Project Details

Project Element	Element Description
Project Title Project Title	Rapid Phenomic Interrogation of CRISPR-Cas9 Edited Mammalian Brains
Principal Investigator Principal Investigator	Chung, Kwanghun
Description Description	Kwanghun Chung, Ph.D., at Massachusetts Institute of Technology will utilize a new genetic manipulation technique called CRISPR to better understand how the brain’s architecture, neuronal connectivity, molecular machinery, and genomic network bring about mental function. Chung aims to overcome certain limitations of CRISPR technology and will use it on mouse brains to ask how genes associated with autism spectrum disorder cause functional, structural, and molecular abnormalities in a cell-type and brain region-specific manner.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	35000
Current Award Period Current Award Period	2016-2018
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	Massachusetts Institute of Technology
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	N/A