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Strategic Plan Cover

IACC Strategic Plan

For Autism Spectrum Disorder Research

2010 Update

Appendices

References

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Durand CM, Betancur C, Boeckers TM, Bockmann J, Chaste P, Fauchereau F, Nygren G, Rastam M, Gillberg IC, Anckarsäter H, Sponheim E, Goubran-Botros H, Delorme R, Chabane N, Mouren-Simeoni MC, de Mas P, Bieth E, Rogé B, Héron D, Burglen L, Gillberg C, Leboyer M, & Bourgeron T. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet. 2007 Jan;39(1):25-7.

Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, & Silva AJ. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med. 2008 Aug;14(8):843-8.

Esch BE & Carr JE. Secretin as a treatment for autism: a review of the evidence. J Autism Dev Disord. 2004 Oct; 34(5):543-56.

Eskenazi B, Marks AR, Bradman A, Harley K, Barr DB, Johnson C, Morga N, & Jewell NP. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ Health Perspect. 2007 May;115(5):792-8.

Forum on Neuroscience and Nervous System Disorders, Institute of Medicine. Autism and the Environment: Challenges and Opportunities for Research, Workshop Proceedings. Washington, DC: The National Academies Press; 2008.

Fujiura GT, Roccoforte JA, & Braddock D. Costs of family care for adults with mental retardation and related developmental disabilities. Am J Ment Retard. 1994 99(3): 250.

Ganz ML. The lifetime distribution of the incremental societal costs of autism. Arch Pediatr Adolesc Med. 2007 Apr;161(4):343-9.

Guy J, Gan J, Selfridge J, Cobb S, & Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science. 2007 Feb 23;315(5815):1143-7.

Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, & Piven J. Magnetic resonance imaging and head circumference study of brain size in autism. Arch Gen Psychiatry. 2005 Dec;62(12):1366-1376.

Hollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E, & Wasserman S. Oxytocin increases retention of social cognition in autism. Biol Psychiatry. 2007 Feb 15;61(4):498-503.

Immunization Safety Review Committee. Immunization Safety Review: Vaccines and Autism. Washington, DC: The National Academies Press; 2004.

Jamain S, Quach H, Betancur C, Råstam M, Colineaux C, Gillberg IC, Soderstrom H, Giros B, Leboyer M, Gillberg C, & Bourgeron T. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet. 2003 May;34(1):27-9.

Järbrink K & Knapp M. The economic impact of autism in Britain. Autism. 2001 Mar;5(1):7-22.

Järbrink K, Fombonne E, & Knapp M. Measuring the parental, service and cost impacts of children with autistic spectrum disorder: A pilot study. J Autism Dev Disord. 2003 33(4), 395-402.

King BH, Hollander E, Sikich L, McCracken JT, Scahill L, Bregman JD, Donnelly CL, Anagnostou E, Dukes K, Sullivan L, Hirtz D, Wagner A, & Ritz L. Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism. Arch Gen Psychiatry. 2009 Jun;66(6):583-90.

Kogan MD, Blumberg SJ, Schieve LA, Boyle CA, Perrin JM, Ghandour RM, Singh GK, Strickland BB, Trevathan E, van Dyck PC. Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics. 2009 Nov;124(5):1395-403.

Kolevzon A, Mathewson KA, & Hollander E. Selective serotonin reuptake inhibitors in autism: a review of efficacy and tolerability. J Clin Psychiatry. 2006 Mar; 67(3):407-14.

Krauss M, Gulley S, Sciegaj M, & Wells N. Access to specialty medical care for children with mental retardation, autism and other special health care needs. Ment Retard. 2003 41(5), 329-339.

Kumar RA, KaraMohamed S, Sudi J, Conrad DF, Brune C, Badner JA, Gilliam TC, Nowak NJ, Cook EH Jr, Dobyns WB, & Christian SL. Recurrent 16p11.2 microdeletions in autism. Hum Mol Genet. 2008 Feb 15;17(4):628-38.

Landa RJ, Holman KC, & Garrett-Mayer E. Social and communication development in toddlers with early and later diagnosis of autism spectrum disorders. Arch Gen Psychiatry. 2007 Jul;64(7):853-64.

Laumonnier F, Bonnet-Brilhault F, Gomot M, Blanc R, David A, Moizard MP, Raynaud M, Ronce N, Lemonnier E, Calvas P, Laudier B, Chelly J, Fryns JP, Ropers HH, Hamel BC, Andres C, Barthélémy C, Moraine C, & Briault S. X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family. Am J Hum Genet. 2004 Mar;74(3):552-7.

Levy SE & Hyman SL. Use of complementary and alternative treatments for children with autistic spectrum disorders is increasing. Pediatr Ann. 2003 Oct;32(10):685-91.

Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, Ecker JR. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009 Nov 19;462(7271):315-22.

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Mandel DS, Ittenbach RF, Levy SE, & Pinto-Martin JA. Disparities in diagnosis received prior to a diagnosis of autism spectrum disorder. J Autism Dev Disord. 2007 Oct; 37(9):1795-1802.

Mandell D, Morales K, Marcus S, Stahmer A, Doshi J, & Polsky D. Psychotropic medication use among children with autism spectrum disorders. Pediatrics. 2008 121(3): e441-448.

Mandell D & Palmer R. Differences among states in the identification of autistic spectrum disorders. Arch Pediatr Adolesc Med. 2005 159(3): 266-269.

Marshall CR, Noor A, Vincent JB, Lionel AC, Feuk L, Skaug J, Shago M, Moessner R, Pinto D, Ren Y, Thiruvahindrapduram B, Fiebig A, Schreiber S, Friedman J, Ketelaars CEJ, Vos YJ, Ficicioglu C, Kirkpatrick S, Nicolson R, Sloman L, Summers A, Gibbons CA, Teebi A, Chitayat D, Weksberg R, Thompson A, Vardy C, Crosbie V, Luscombe S, Baatjes R, Zwaigenbaum L, Roberts W, Fernandez B, Szatmari P, & Scherer SW. Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet. 2008 Feb;82(2):477-488.

McClannahan LE, MacDuff GS, & Krantz PJ. Behavior analysis and intervention for adults with autism. Behav Modif. 2002 Jan;26(1):9-26.

McVicar KA, Ballaban-Gil K, Rapin I, Moshé SL, & Shinnar S. Epileptiform EEG abnormalities in children with language regression. Neurology. 2005 Jul 12;65(1):129-31.

Montes G & Halterman JS. Association of childhood autism spectrum disorders and loss of family income. Pediatrics. 2008 Apr;121(4):e821-6.

Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, & LaSalle JM. A MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008, 1(3):169-78.

Palmer R, Blanchard S, Jean C, & Mandell D. School district resources and identification of children with autistic disorder. Am J Public Health. 2005 95(1):125-130.

Palmer RF, Blanchard S, Stein Z, Mandell D, & Miller C. Environmental mercury release, special education rates, and autism disorder: an ecological study of Texas. Health Place. 2006 Jun;12(2):203-9.

Palmer RF, Blanchard S, & Wood R. Proximity to point sources of environmental mercury release as a predictor of autism prevalence. Health Place. 2009 Mar;15(1):18-24.

Pardo CA, Vargas DL, & Zimmerman AW. Immunity, neuroglia and neuroinflammation in autism. Int Rev Psychiatry. 2005 Dec;17(6):485-95.

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Ruble L, Heflinger C, Renfrew J, & Saunders R. Access and service use by children with autism spectrum disorders in Medicaid managed care. J Autism Dev Disord. 2005 35(1):3-13.

Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimäki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, & Wigler M. Strong association of de novo copy number mutations with autism. Science. 2007 Apr 20;316(5823):445-9.

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About the IACC

The Interagency Autism Coordinating Committee (IACC) was established by Congress under the Combating Autism Act of 2006 (CAA) to provide advice to the Secretary of Health and Human Services (HHS) and coordinate all efforts within HHS concerning autism spectrum disorders (ASD).

As mandated by law, the IACC has a membership composed of federal officials from agencies involved in autism research and services and public members, including people with ASD, parents of children and adults with ASD and members of the autism advocacy and research community. The diversity of the committee ensures that a broad range of views and opinions is reflected and discussed in a public forum.

Under the CAA, the IACC is required to: (1) Develop and annually update a strategic plan for ASD research, (2) develop and annually update a summary of advances in ASD research, and (3) monitor federal activities related to ASD.

In completing the first IACC Strategic Plan for Autism Spectrum Disorder Research in 2009 and releasing this first update of the plan in 2010, the IACC has laid out a framework for the pursuit of critical biomedical and services research. Through activities such as public meetings and workshops, publication of an annual Summary of Advances in ASD Research, dissemination of information regarding ASD research and IACC activities, gathering of public input and coordination of federal activities related to autism, the IACC continues in its effort to provide guidance to the Department of Health and Human Services and to reach out to the broader autism community to find ways to work together to help people with autism and their families.

IACC Member Roster

Chair

  • Thomas R. Insel, M.D.
    Director
    National Institute of Mental Health
    National Institutes of Health
    Bethesda, Maryland

Federal Members

  • James F. Battey, M.D., Ph.D.
    Director
    National Institute on Deafness and
    Other Communication Disorders
    National Institutes of Health
    Bethesda, Maryland
  • Linda Birnbaum, Ph.D.
    Director
    National Institute of Environmental Health Sciences
    National Institutes of Health
    Research Triangle Park, North Carolina
  • Ellen W. Blackwell, M.S.W.
    Division of Community and Institutional Services
    Disabled and Elderly Health Programs Group
    Center for Medicaid and State Operations
    Centers for Medicare and Medicaid Services
    Baltimore, Maryland
  • Henry Claypool
    Director
    Office on Disability
    U.S. Department of Health and Human Services
    Washington, DC

  • Francis S. Collins, M.D., Ph.D.
    Director
    National Institutes of Health
    Bethesda, Maryland
  • Alan E. Guttmacher, M.D.
    Acting Director
    Eunice Kennedy Shriver National Institute
    of Child Health and Human Development
    National Institutes of Health
    Bethesda, Maryland
  • Gail R. Houle, Ph.D.
    Associate Division Director
    Research-to-Practice Division
    Early Childhood Programs 
    Office of Special Education Programs
    U.S. Department of Education
    Washington, DC
  • Larke N. Huang, Ph.D.
    Senior Advisor on Children
    Office of the Administrator
    Substance Abuse and Mental Health Services Administration
    Rockville, Maryland
  • Jennifer G. Johnson, Ed.D.
    Program Specialist
    Administration on Developmental Disabilities
    Administration for Children and Families
    Washington, DC
  • Walter J. Koroshetz, M.D.
    Deputy Director
    National Institute of Neurological
    Disorder and Stroke
    National Institutes of Health
    Bethesda, Maryland
  • Edwin Trevathan, M.D., M.P.H.
    Director, National Center on Birth Defects and Developmental Disabilities
    Centers for Disease Control and Prevention
    Atlanta, Georgia
  • Peter van Dyck, M.D., M.P.H.
    Associate Administrator
    Maternal and Child Health
    Health Resources and Services Administration
    Rockville, Maryland

Public Members

  • Lee Grossman
    President and CEO
    Autism Society of America
    Bethesda, Maryland
  • Yvette M. Janvier, M.D.
    Medical Director
    Children's Specialized Hospital
    Toms River, New Jersey
  • Christine M. McKee, J.D.    
    Rockville, Maryland

  • Lyn Redwood, RN, M.S.N.  
    Co-Founder and Vice President
    Coalition for Safe Minds
    Tyrone, Georgia
  • Stephen M. Shore, Ed.D.
    Executive Director
    Autism Spectrum Consulting
    Newton, Massachusetts
  • Alison Tepper Singer, M.B.A.
    President
    Autism Science Foundation
    New York, New York

Office of Autism Research Coordination (OARC) Staff List

  • Della M. Hann, Ph.D.
    Acting Director
  • Susan A. Daniels, Ph.D.
    Deputy Director
  • Erin H. Bryant, M.J.
    Science Writer/Editor
  • Nicole Jones
    Web Developer
  • Monica P. Mallampalli, Ph.D.
    Science Policy Analyst
  • Miguelina Perez
    Program Specialist
  • Sarah E.V. Rhodes, Ph.D.
    Detailee, NIMH Intramural Research Program

Copyright Information
All material appearing in this report is in the public domain and may be reproduced or copied. A suggested citation follows.

Suggested Citation
Interagency Autism Coordinating Committee (IACC). IACC Strategic Plan for Autism Spectrum Disorder (ASD) Research —2012 Update. December 2012. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: http://iacc.hhs.gov/strategic-plan/2012/index.shtml.

Appendices

 
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